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Gilead’s remdesivir prevents lung damage in COVID-19 study on monkeys

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Gilead’s remdesivir prevents lung damage in COVID-19 study on monkeys
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Gilead Sciences Inc’s antiviral drug remdesivir prevented lung illness in macaque monkeys contaminated with the brand new coronavirus, based on a research printed within the journal Nature on Tuesday.

The findings have been first reported in April by the US National Institutes of Health (NIH) as a “preprint,” previous to conventional tutorial validation offered by a medical journal.

Remdesivir is the primary drug proven to be efficient in opposition to COVID-19 in human trials. Other medical research involving the drug are being intently watched as nations search for remedies for the illness that has contaminated greater than 7 million folks and killed over 400,000 globally.

Remdesivir was permitted final month in Japan underneath the model identify Veklury. It has been cleared for emergency use in severely-ill sufferers within the United States, India and South Korea. Some European nations are additionally utilizing it underneath compassionate applications.

In the research printed on Tuesday, 12 monkeys have been contaminated with the brand new coronavirus, and half of them got early therapy with remdesivir.

Macaques that obtained remdesivir didn’t present indicators of respiratory illness and had decreased injury to the lungs.

Authors of the research additionally stated the viral load, or quantity of virus, within the lungs of remdesivir-treated animals was decrease.

The authors urged that remdesivir ought to be thought-about as a therapy as early as potential to forestall development to pneumonia in COVID-19 sufferers.

In a US-run medical trial launched in late April, remdesivir decreased hospitalization stays by 31%, or about 4 days, in comparison with a placebo.

Gilead final week reported information from its personal trial of remdesivir, exhibiting that the drug offered a modest profit for sufferers with average COVID-19 given a five-day course of the therapy.

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